Omega XL and Relief Factor are both sold directly by their makers as supplements for everyday aches. Omega XL is a softgel built on green-lipped mussel oil, and its maker markets it for joint and muscle support. Relief Factor is a 60-packet supplement its maker markets for temporary relief of minor aches and pains. Below is what each maker says, what the research on the key ingredient covers, and the price and refund terms to check before you buy.
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Omega XL vs Relief Factor at a glance
| Point | Omega XL | Relief Factor |
|---|---|---|
| Who sells it | Great HealthWorks, per its site footer and guarantee page | Relief Factor, per its homepage |
| Stated purpose | ‘Joint & Muscle Support’, with ‘Enhances joint mobility’ on its banner | ‘Support for temporary relief of minor aches and pains’ |
| Form and count | Softgels; 60, 120 or 300 count per its guarantee page | 60 packets per its homepage |
| Dose per serving | 8 to 12 green-lipped mussels per softgel, per its homepage; the milligrams per serving are on the Supplement Facts panel | See the Supplement Facts panel on the package |
| Price (homepage capture, October 20, 2026) | Offer banner shows a value of $115.80 and a price of $49.95 for a Buy 1 Get 2 Free bundle, first order with auto-ship | Check today’s price with the company |
| Shipping | Free shipping on orders $49 and up | Check the Shipping Policies link in the footer |
| Refund window | 30 days from first purchase, bought direct, for new customers | Check the Returns Policy link in the footer |
| Maker’s own rating figure | 4.7, shown beside a reviews label on its homepage | Customer quotes and a claim of over one million customers |
| Maker’s disclaimer | ‘These statements have not been evaluated by the FDA.’ | ‘These statements have not been evaluated by the Food and Drug Administration… Individual results may vary.’ |
What each product is and who sells it
Omega XL’s site names Great HealthWorks as the company behind it, and its footer lists a Florida street address. A TV offer banner on the same site describes the product as made by Gruut Health/Nutra, so its own pages name two different companies. Ask support which company is the seller before you order.
Omega XL’s homepage describes a softgel of green-lipped mussel oil from New Zealand, with each softgel holding the oils of 8 to 12 mussels. It says the softgels are small and easy to swallow, with no fishy aftertaste or burps, and that the company has sold millions of bottles since 2003. These are the maker’s own statements.
Relief Factor’s homepage presents its pain product as a 60-packet dietary supplement for temporary relief of minor aches and pains. The line is also described as ‘100% Drug-Free Supplements’, and the homepage says over one million customers have chosen them. The pain product carries the heading ‘You Deserve a Pain-Free Life.’ One customer quoted on the page, Art D., says: ‘When you have pain for 6 years and start taking Relief Factor and start feeling pain free you can’t believe it.’
What is in each one
Omega XL’s ingredient is green-lipped mussel oil extract. The amount per softgel and per daily dose is on the Supplement Facts panel, so read that panel before you buy and note the milligrams you would take each day.
For Relief Factor, read the Supplement Facts panel on the packet for every ingredient and amount. Then check each ingredient against its studies, not just the front-of-box claim. when product claims outrun the research explains how to make that comparison.
What the research says about the mussel ingredient
The 2013 paper on this extract is a study protocol in Nutrition Journal, hosted by the U.S. National Library of Medicine’s PubMed Central. It names Lyprinol/Omega XL as a form of the same extract, PCSO-524. It describes a planned trial in children with attention and hyperactivity symptoms and reports no results, so it is a trial plan rather than evidence of outcomes. It also says the study was supported by a grant from Pharmalink International. You can read it in the 2013 PCSO-524 study protocol.
For joint pain, the closest evidence summary is ConsumerLab’s review of the freeze-dried mussel powder and green-lipped mussel omega-3s. The full answer is in ConsumerLab’s arthritis supplement answer.
Who should not use Omega XL, and what about kidneys or liver?
The 2013 protocol excluded children with a shellfish allergy or other food allergies, heart disease, high blood pressure, diabetes, kidney disease, liver disease, or pregnancy or breastfeeding. It also excluded children currently taking medication, other than stimulants where an ADHD diagnosis was present. Those are a trial’s screening rules, not a safety ruling for adults, but they show who the research team chose to keep out.
If you are asking about kidneys or liver, take that question to your clinician before you start. For what omega-3 trials report about side effects, see omega-3 side effects in studies.
Ask a clinician or pharmacist before starting either product if you have a shellfish allergy, a kidney or liver condition, or take any prescription medicine. Relief Factor’s ingredients are on its packet, so the pharmacist can check them against your list.
What does each one cost?
Prices and bundles change, so check today’s price directly with each company. On its homepage captured October 20, 2026, Omega XL’s TV offer banner shows a value of $115.80 and a price of $49.95 for a Buy 1 Get 2 Free bundle. The banner lists two OmegaXL bottles and one Vitamin XL D3 bottle (1,000 IU per the banner). The footnote says the $49.95 price applies only to a first order with monthly auto-ship.
The bundle does not give one clean per-bottle price, so use the checkout price for a single bottle. Then divide that price by the number of softgels in your daily dose, which the label gives. For Relief Factor’s price, check its product page or call sales at 888-488-3112.
Refunds, guarantees and cancelling
Omega XL’s money-back guarantee covers new customers who buy directly from the company by phone or on its site, and who live in the United States or Canada. Its terms say:
- Return within 30 days of your first purchase for a refund, less shipping and handling.
- Return limits are up to four 60-count bottles, two 120-count bottles, or one 300-count bottle.
- If you are on auto-ship, cancel within 30 days of your first auto-ship purchase, then return the bottles no later than 15 days after you cancel.
- If you are not on auto-ship, return no later than 35 days after your first purchase.
- You pay return shipping in advance. Cash-on-delivery returns are not accepted.
- Free or promotional bottles, including Buy One Get One extras, must go back in the same package as the paid bottle.
- Orders bought from a retailer or online marketplace fall outside this guarantee.
Its guarantee page says refunds can take up to 30 days after the company receives the return. Relief Factor’s refund terms sit on its Returns Policy page, linked from its footer. Read that page and its Shipping Policies page before you buy.
What buyers say
Omega XL’s homepage shows a 4.7 figure beside a reviews label and claims over 30,000 five-star reviews, on the October 20, 2026 capture. One quote on the page, from Connie, reads: ‘I enjoy every moment with my grandkids thanks to OmegaXL.’ Relief Factor’s homepage says over one million customers have chosen it and shows several customer quotes. Both sets of figures and quotes come from the makers. They are not third-party ratings.
Does Omega XL really stop joint pain?
Omega XL’s own wording is ‘Enhances joint mobility’, alongside ‘Joint & Muscle Support’. That describes movement support, not a promise that pain stops. The research on the mussel oil is mixed, as ConsumerLab’s summary above shows.
Track it yourself. Pick one time each day, rate your stiffness from 0 to 10, and note how far you walk. Bring that log to your clinician after several weeks so you both can judge whether anything is changing.
Is anything better than Omega XL for joint pain?
ConsumerLab’s arthritis answer does not rank products. It sorts ingredients by what studies found. For osteoarthritis, its ‘might help’ list includes collagen hydrolysate, boswellia, ashwagandha extract and ginger. It names curcumin, cat’s claw and rose hips as having evidence for both osteoarthritis and rheumatoid arthritis. Its ‘might not help’ list includes glucosamine and chondroitin for knee osteoarthritis, where more recent and larger studies show little or no benefit, and fish oil.
For a wider set of joint options, see Joint, Muscle and Bone Care on this site. If you are weighing collagen, collagen peptides for joint support covers that ingredient in more detail.
Does Omega XL help with lower back pain?
Omega XL presents its product as joint and muscle support, not as a back-pain product. If back pain is your main problem, start with what is the best product for back pain and compare options there.
Do doctors recommend Omega XL?
Omega XL’s About page lists a Chief Science Officer among its company staff. That is a company role, not an outside doctor’s recommendation. To find out whether a clinician would suggest it for you, ask your own doctor and bring the label.
What is the downside of Omega XL?
- The research on the mussel oil for joint pain is mixed, according to ConsumerLab.
- The $49.95 bundle price shown on the capture is a first-order offer with monthly auto-ship; later orders may be priced differently.
- Refund timing is tight. You have 30 days from first purchase, must cancel auto-ship within 30 days and return within 15 days after cancelling, and pay return shipping.
- Free bundle bottles must go back with the paid bottle.
- Orders bought through a retailer or marketplace are outside its guarantee.
Which one suits your situation?
- If you want one named ingredient, green-lipped mussel oil in a softgel, with a joint-mobility focus on the label, Omega XL matches that description.
- If you want a packet product its maker markets for temporary relief of minor aches and pains, Relief Factor matches that description.
- If the refund window matters most, Omega XL’s terms are written out in full on its site. Read Relief Factor’s Returns Policy before you buy.
- If you are weighing the bundle, make sure you know the cancel-by date before the first auto-ship order ships.
Before you order
- Check the Supplement Facts panel on each product for the amount per dose and the number of doses per day.
- Ask support which company is the seller, since Omega XL’s pages name two.
- Write down your cancel-by date if you choose auto-ship.
- Read Relief Factor’s Returns Policy and Shipping Policies pages from its footer.
- Check today’s price with each company. Omega XL customer service is 1-800-488-8082, Monday to Friday, 9:00am to 5:30pm EST. Relief Factor sales is 888-488-3112.
- Ask your clinician about any medicine you take, a shellfish allergy, or a kidney or liver condition.
By BackToHealthTroy.com Editorial Team
This article is for general information purposes only and does not constitute medical advice. Consult your doctor or qualified healthcare provider before making changes to your health routine.